Coumadin and Plavix are both anti-platelet agents as well as aspirin. The most widely studied and prescribed antiplatelet agent for the prevention of stroke and other serious vascular events among high vascular risk patients is aspirin. Read about clopidogrel bisulfate (Plavix) a drug to prevent heart attacks, strokes, and to treat peripheral vascular disease and claudication. Plavix is an anti-platelet blood clotting prevention drug. Promptly spotting stroke symptoms leads to faster treatment and less damage to the brain. Read about transient ischemic attack (TIA) or mini-stroke symptoms such as the inability to feel or move one side of the body, speech and vision difficulties, confusion, and the inability to follow commands. If you have a moderately or severely narrowed neck (carotid) artery, your doctor may suggest carotid endarterectomy (end-ahr-tur-EK-tuh-me). This preventive surgery clears carotid arteries of fatty deposits (atherosclerotic plaques) before another TIA or stroke can occur. Drug Name Other Names Used For Drug Type Aspirin acetylsalicylic acid, ASA Stroke prevention Antiplatelet Clopidogrel Plavix® Stroke prevention Antiplatelet Responders were subjects who showed one or more new infarctions on MRI since screening, or experienced a confirmed recurrent stroke, through 24 months (913 days). A transient ischemic attack (TIA) is a brief interruption of blood flow to part of the brain that causes temporary stroke-like symptoms. The risks for TIA are the same as for heart attack, stroke, and peripheral artery disease, and include smoking, high blood pressure, high cholesterol, diabetes, and family history. A thrombotic stroke occurs when part of the brain gets injured because the artery that normally supplies blood to it gets blocked. This causes the blood flow to be reduced or stopped completely. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Bakhadirov on substitution for eliquis: If you have atrial fibrillation better use an anticoagulant, Eliquis. Plavix (clopidogrel) is an antiplatlet drug, two different mechanisms, discuss with your doctor, wish you wellness.